The story follows Ye Ping'an, a heart doctor who arrives in Shengdu to investigate an old case. Rumors spread that she manipulates hearts and minds, earning her the title of "witch." When a sudden murder occurs, she's accused of the crime. Yuan Shaocheng, an ambitious official, realizes there's more to the case yet still seeks to have her executed. But Ye Ping'an has already made her first move on the path to vengeance.